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Myositis complicating benzathine penicillin-G injection in a case of rheumatic heart disease

A 7-year old boy developed myositis secondary to intramuscular injection of benzathine penicillin-G in the context of secondary prophylaxis for RF

Citation: 
Francis JR, Wyber R, Remenyi B, Croser D, Carapetis J. Myositis complicating benzathine penicillin-G injection in a case of rheumatic heart disease. IDCases. 2016 Feb 15;4:6-7.

Keywords:
Acute rheumatic fever, Adverse drug reaction, Penicillin, Rheumatic heart disease

Abstract:
A 7-year old boy developed myositis secondary to intramuscular injection of benzathine penicillin-G in the context of secondary prophylaxis for rheumatic heart disease. Side effects of intramuscular delivery of benzathine penicillin-G are well described and include injection site pain and inflammation, but myositis, as depicted on magnetic resonance imaging in this case, has not previously been described.