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Azithromycin mitigates human rhinovirus impact on barrier integrity and function in non-diseased airway epithelium

Azithromycin improves symptomology in various chronic airway diseases exacerbated by viral infections. However, the mechanisms underlying the apparent antiviral effects of azithromycin remain unclear.

Citation:
Looi K, Sutanto EN, Iosifidis T, Berry LJ, Kicic A, Stick SM. Azithromycin mitigates human rhinovirus impact on barrier integrity and function in non-diseased airway epithelium. Frontiers in Cell and Developmental Biology. 2025;13.

Keywords:
Airway epithelium; azithromycin; barrier function; human rhinovirus; tight junction

Abstract:
Azithromycin improves symptomology in various chronic airway diseases exacerbated by viral infections. However, the mechanisms underlying the apparent antiviral effects of azithromycin remain unclear.