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Maternal and neonatal outcomes after infection with monkeypox virus clade I during pregnancy in DR Congo: a pooled, prospective cohort study

Monkeypox virus (MPXV) has been linked to vertical transmission, but systematic data are scarce. We aimed to describe the sociodemographic, clinical, and virological characteristics and assess the frequency and determinants of adverse outcomes in pregnant women with MPXV clade I infection. 

Citation:
Vakaniaki EH, Barhishindi I, ……. Braunack-Mayer L, Nganga B, et al. Maternal and neonatal outcomes after infection with monkeypox virus clade I during pregnancy in DR Congo: a pooled, prospective cohort study. Lancet. 2026;407(10525):256-66.

Keywords:
Epidemiology; spontaneous abortion; infant; newborn; monkeypox virus; complications; transmission; pregnancy; virology; stillbirth; Democratic Republic of the Congo

Abstract:
Monkeypox virus (MPXV) has been linked to vertical transmission, but systematic data are scarce. We aimed to describe the sociodemographic, clinical, and virological characteristics and assess the frequency and determinants of adverse outcomes in pregnant women with MPXV clade I infection.