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Research

Arsenic and respiratory disease

Arsenic is the only environmental toxin that has been linked to both malignant and nonmalignant respiratory disease following ingestion, rather than inhalation, making arsenic a unique toxicant to the respiratory system. Chronic exposure to arsenic has been associated with the development of respiratory symptoms, impaired lung function, and chronic lung disease.

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Early surveillance of infants and preschool children with cystic fibrosis

Sensitive and non-invasive surveillance tools are needed for the clinical management of infants and preschool children with cystic fibrosis (CF). The lung clearance index from the multiple breath washout and functional and morphological outcomes from magnetic resonance imaging provide promising alternatives to current gold standard techniques. Early detection and treatment of lung disease during this important period offers the opportunity to improve the quality of life for individuals with CF.

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Early respiratory viral infections in infants with cystic fibrosis

Early viral infections were associated with greater neutrophilic inflammation and bacterial pathogens

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Effect of Albuterol Premedication vs Placebo on the Occurrence of Respiratory Adverse Events in Children Undergoing Tonsillectomies: The REACT Randomized Clinical Trial

Determine whether inhaled albuterol sulfate (salbutamol sulfate) premedication decreases the risk of perioperative respiratory adverse events

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Identifying pediatric lung disease: A comparison of forced oscillation technique outcomes

These findings suggest the utility of specific FOT outcomes is dependent on the respiratory disease being assessed

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Parents welcome follow-up using mobile devices: A survey of acceptability at an Australian tertiary paediatric centre

We surveyed 642 parents and carers at Perth Children's Hospital, targeting demographics, device ownership and attitudes towards electronic follow-up

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Increased prevalence of expiratory flow limitation during exercise in children with bronchopulmonary dysplasia

Expiratory flow limitation is more prevalent in children born preterm with bronchopulmonary dysplasia and is associated with airway obstruction

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Persistent and progressive long-term lung disease in survivors of preterm birth

This review aims to summarise what is known about the long-term pulmonary outcomes of contemporary preterm birth

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Deep or awake removal of laryngeal mask airway in children at risk of respiratory adverse events undergoing tonsillectomy - a randomised controlled trial

We found no evidence for a difference in the timing of the laryngeal mask airways removal on the incidence of respiratory adverse events

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End-inspiratory molar mass step correction for analysis of infant multiple breath washout tests

We aimed to evaluate the use of the EIMM-step method in a broad range of infants.