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News & Events
Shopping For Data to Drive DiscoveriesWhat if researchers could shop for different data to help uncover how, when and why chronic conditions such as asthma, obesity, allergies and poor mental health develop?
News & Events
ORIGINS Ch7 News StoryORIGINS featured on Channel 7 News recently with two family stories of how ORIGINS changed their lives.
News & Events
Tips for protecting your baby in the summer heatPaediatrician Dr Lana Bell shares her top tips for keeping your baby or toddler cool, well-hydrated and protected as the temperature soars.
News & Events
Prospective Student EveningStudents met ORIGINS team at the recent Prospective Student Evening at Telethon Kids Institute.
News & Events
Hong Kong researcher highlights importance of nature for children during Joondalup Health Campus visitJoondalup Health Campus welcomed international researcher Dr Tanja Sobko to share her research on the link between mental health and time spent in nature.
News & Events
Early ORIGINS: Disease prevention starts with the early yearsThe Joondalup Health Campus and The Kids are investigating how childhood and adult-onset diseases can be prevented during foetal development and in the early years of life.
Research
Urinary Ferritin as a Noninvasive Means of Assessing Iron Status in Young ChildrenIron deficiency (ID) is the most common nutritional deficiency affecting young children. Serum ferritin concentration is the preferred biomarker for measuring iron status because it reflects iron stores; however, blood collection can be distressing for young children and can be logistically difficult. A noninvasive means to measure iron status would be attractive to either diagnose or screen for ID in young children.
Research
Beyond Plants: The Ultra-Processing of Global Diets Is Harming the Health of People, Places, and PlanetGlobal food systems are a central issue for personal and planetary health in the Anthropocene. One aspect of major concern is the dramatic global spread of ultra-processed convenience foods in the last 75 years, which is linked with the rising human burden of disease and growing sustainability and environmental health challenges.
Research
PKC activation promotes maturation of cord blood T cells towards a Th1 IFN-γ propensityA significant number of babies present transiently with low protein kinase C zeta (PKCζ) levels in cord blood T cells, associated with reduced ability to transition from a neonatal Th2 to a mature Th1 cytokine bias, leading to a higher risk of developing allergic sensitisation, compared to neonates whose T cells have 'normal' PKCζ levels. However, the importance of PKCζ signalling in regulating their differentiation from a Th2 to a Th1 cytokine phenotype propensity remains undefined.