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Research
BCG-Induced Immune Training: Interplay between Trained Immunity and Emergency GranulopoiesisBacille Calmette-Guérin (BCG) is the most commonly administered vaccine in human history. The medical application of BCG extends far beyond the fight against tuberculosis. Despite its stellar medical record over 100 years, insight into how BCG provides this vast range of benefits is largely limited, both for its pathogen-specific (tuberculosis) as well as pathogen-agnostic (other infections, autoimmunity, allergies, and cancer) effects.
Research
Airway-associated adipose tissue accumulation is increased in a kisspeptin receptor knockout mouse modelAirway-associated adipose tissue increases with body mass index and is a local source of pro-inflammatory adipokines that may contribute to airway pathology in asthma co-existing with obesity. Genetic susceptibility to airway adiposity was considered in the present study through kisspeptin/kisspeptin receptor signalling, known to modulate systemic adiposity and potentially drive airway remodelling.
Research
Identifying the asthma research priorities of people with asthma, their carers and other stakeholdersPeople living with asthma, their carers, clinicians and policymakers are the end-users of research and need research that address their individual healthcare needs. We aimed to understand the research priorities of end-users of asthma research.
Research
Editorial: The relationship between puberty and immune-driven diseaseThe way the immune system operates differs between males and females. This is due to both differential expression of immune-related genes from the sex chromosomes as well as the immune modulatory properties of sex hormones. Together, these effects contribute to a skewed prevalence of disease and disease course between males and females, including allergic-, infectious-, autoimmune-, and cancerous disease.
News & Events
The Kids researchers awarded Raine Medical Research Foundation fundingCongratulations to Dr Gail Alvares and Dr Rachel Foong, who have been awarded funding from the Raine Medical Research Foundation.
News & Events
National Asthma Week: 10 things you need to know about asthmaAsthma affects about half a million Australian children and is one of the most common reasons why kids need to see a doctor or go to emergency.
News & Events
Every Thursday: Discussion & Technical Seminar SeriesImproving health outcomes for pregnant women with allergic asthma and their babies: Thursday 22nd May.
News & Events
Trying to beat asthma caused by exerciseProfessor Graham Hall is leading a study looking at exercise-related asthma in young children, and we need volunteers to take part.
News & Events
Telethon Institute research provides new insights into the cause of asthma attacksTelethon Institute for Child Health Research scientist Dr Anthony Bosco has been recognised for his cutting edge research investigating asthma attacks