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Research

The effect of functioning on Quality of Life Inventory-Disability measured quality of life is not mediated or moderated by parental psychological distress

The measurement of quality of life (QOL) in children with intellectual disability often relies upon proxy report via caregivers. The current study investigated whether caregiver psychological distress mediates or moderates the effects of impairment on their ratings of QOL in children with intellectual disability.

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Pre-emptive intervention versus treatment as usual for infants showing early behavioural risk signs of autism spectrum disorder

A pre-emptive intervention for the autism spectrum disorder prodrome had no immediate treatment effect on early autism spectrum disorder symptoms

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Do hypertensive diseases of pregnancy disrupt neurocognitive development in offspring?

The current study sought to determine whether gestational hypertension and pre-eclampsia are associated with neurocognitive outcomes in middle childhood.

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What bridges the gap between self-harm and suicidality? The role of forgiveness, resilience and attachment

There is a lack of understanding of why some people who self-harm escalate to suicidal behaviour when others do not. Psychological factors such as attachment...

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The perinatal androgen to estrogen ratio and autistic-like traits in the general population: a longitudinal pregnancy cohort study.

While previous studies have found a link between testosterone levels in amniotic fluid and autistic-like traits, a similar relationship has not been found...

Research

Do hypertensive diseases of pregnancy disrupt neurocognitive development in offspring?

Do hypertensive diseases of pregnancy disrupt neurocognitive development in offspring?

Research

Modelling quality of life in children with intellectual disability using regression trees

To identify factors associated with quality of life (QoL) in children with intellectual disability. We aimed to identify patterns of association not observable in previous hypothesis-driven regression modelling using the same data set from a cross-sectional observational study.

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Genetic counseling as preventive intervention: toward individual specification of transgenerational autism risk

Although autism spectrum disorders (ASD) are among the most heritable of all neuropsychiatric syndromes, most affected children are born to unaffected parents. Recently, we reported an average increase of 3-5% over general population risk of ASD among offspring of adults who have first-degree relatives with ASD in a large epidemiologic family sample.

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Vitamin D is crucial for maternal care and offspring social behaviour in rats

These data highlight that early life levels of vitamin D are an important consideration for maternal behavioural adaptations as well as offspring neuropsychiatry

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Cytokine levels and associations with symptom severity in male and female children with autism spectrum disorder

ASD's are complex, pervasive and heterogeneous neurodevelopmental conditions with varying conditions, trajectories, significant male bias and unknown etiology.