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Research

Interferon regulatory factor 7 regulates airway epithelial cell responses to human rhinovirus infection

IRF7 regulates the expression of genes involved in antiviral immunity, inflammation, and the response to oxidative stress during HRV infections in HBE cells

Research

School policies on bullying and cyberbullying: perspectives across three Australian states

The perspectives of professionals involved in bullying and cyberbullying policy construction, across three different Australian states

Research

Cerebral palsy and perinatal mortality after pregnancy-induced hypertension across the gestational age spectrum: Observations of a reconstructed total population cohort

This reconstructed total population cohort paper investigates the relationship between cerebral palsy & pregnancy induced hypertension.

Research

ViPAR: A software platform for the Virtual Pooling and Analysis of Research Data

ViPAR is a secure, flexible and powerful analysis platform built on open source technology that is currently in use by large international consortia

Research

Autonomic nervous system dysfunction in psychiatric disorders and the impact of psychotropic medications: A systematic review and meta-analysis

Findings confirm substantial reductions in heart rate variability across psychiatric disorders, and remained significant even in medication-free individuals

Research

Nurses are underutilised in antimicrobial stewardship - Results of a multisite survey in paediatric and adult hospitals

Nurses consider antimicrobial stewardship activities within their roles, but are underutilised in antimicrobial stewardship programs

Research

Comprehending the Health Informatics Spectrum: Grappling with System Entropy and Advancing Quality Clinical Research

We outline three scenarios from across the health spectrum where issues with health informatics are exemplified.

Research

CFTR-dependent defect in alternatively-activated macrophages in cystic fibrosis

CFTR-dependent imbalance of macrophage phenotypes and functions could contribute to the exaggerated inflammatory response seen in CF lung disease

Research

PGE2 pulsing of murine bone marrow cells reduces migration of daughter monocytes/macrophages in vitro and in vivo

Our results reveal long-lasting changes to progenitor cells of monocytes/macrophages by a 2-hour dimethyl PGE2 pulse that, in turn, limits the migration of their daughter cells to chemoattractants and inflammatory mediators.

Research

Conditionally reprogrammed primary airway epithelial cells maintain morphology, lineage and disease specific functional characteristics

Here, we show that conditionally reprogrammed airway epithelial cells (CRAECs) can be established from both healthy and diseased phenotypes.