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Initial acquisition and succession of the cystic fibrosis lung microbiome is associated with disease progression in infants and preschool children

Initial acquisition and succession of the cystic fibrosis lung microbiome is associated with disease progression in infants and preschool children

Assessment of p.Phe508del-CFTR functional restoration in pediatric primary cystic fibrosis airway epithelial cells

Assessment of p.Phe508del-CFTR functional restoration in pediatric primary cystic fibrosis airway epithelial cells Abstract Background Mutations in

The potential of antisense oligonucleotide therapies for inherited childhood lung diseases

The potential of antisense oligonucleotide therapies for inherited childhood lung diseases Antisense oligonucleotides (AOs) are an emerging

Oxidative stress and abnormal bioactive lipids in early cystic fibrosis lung disease

Oxidative stress and abnormal bioactive lipids in early cystic fibrosis lung disease. What did you find? We focused on lipid molecules which we know

The effect of 100% oxygen on tidal breathing parameters in preschool children

The effect of 100% oxygen on tidal breathing parameters in preschool children Does 100% oxygen change the way children breathe? The multiple breath

News & Events

$3.4mill to improve treatment management of cystic fibrosis

The Kids researchers have been awarded over $3.4 million for a new trial to pioneer improved ways for managing cystic fibrosis (‘CF’).

Ivacaftor or lumacaftor/ivacaftor treatment does not alter the core CF airway epithelial gene response to rhinovirus

We tested the hypothesis that treatment of CF epithelial cells with ivacaftor (Iva) or ivacaftor/lumacaftor (Iva/Lum) would improve control of rhinovirus infection.

AREST CF (Cystic Fibrosis)

Promoting healthier lives for children with Cystic Fibrosis

Consumer Reference Group

A clinical trial is a scientific study, or an organised test of medicines and new treatment options, involving patient and non-patient human volunteers.

Lung inflammation and simulated airway resistance in infants with cystic fibrosis

Lung inflammation and simulated airway resistance in infants with cystic fibrosis Cystic fibrosis (CF) is characterized by small airway disease; but