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Research

Tonsil organ model to evaluate carriage, disease mechanisms and therapeutic interventions for treatment and prevention of GAS infections

Tim Barnett PhD Head, Strep A Pathogenesis and Diagnostics timothy.barnett@thekids.org.au Head, Strep A Pathogenesis and Diagnostics Tim has worked

Research

Strongyloides seroprevalence before and after an ivermectin mass drug administration in a remote Australian Aboriginal community

We report the impact on Strongyloides seroprevalence after two oral ivermectin mass drug administrations (MDAs) delivered 12 months apart in a remote Australian Aboriginal community.

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Group A streptococcal pharyngitis: Immune responses involved in bacterial clearance and GAS-associated immunopathologies

Innate and adaptive host immune responses are fundamental for defense against streptococcal pharyngitis and are central to the clinical manifestation of disease.

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Impact of heart disease on maternal, fetal and neonatal outcomes in a low-resource setting

Occult maternal heart disease may be responsible for a substantial proportion of adverse pregnancy outcomes in low-resource settings

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The end rheumatic heart disease in Australia study of epidemiology (ERASE) project: Data sources, case ascertainment and cohort profile

The ERASE Project has created an unprecedented linked administrative database on acute rheumatic fever and rheumatic heart disease in Australia

Research

SToP (See, Treat, Prevent) skin sores and scabies trial: study protocol for a cluster randomised, stepped-wedge trial for skin disease control in remote Western Australia

Skin infection burden in remote Aboriginal communities can be reduced by the See, Treat, Prevent (SToP skin sores and scabies) trial

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Clinical outcomes for young people with screening-detected and clinically-diagnosed rheumatic heart disease in Fiji

Young people with screening-detected RHD have worse health outcomes than screen-negative cases in Fiji.

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Hospital admissions for skin infections among Western Australian children and adolescents from 1996 to 2012

The objective of this study was to describe the occurrence of skin infection associated hospitalizations in children born in Western Australia (WA).

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Hospital admissions for skin infections among Western Australian children and adolescents from 1996 to 2012

Skin infections are a significant cause of severe disease, requiring hospitalization in Western Australian children, particularly with Aboriginal children