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Research

Health service utilisation for acute respiratory infections in infants graduating from the neonatal intensive care unit: a population-based cohort study

Despite advances in neonatal intensive care, babies admitted to Neonatal Intensive Care Units (NICU) suffer from adverse outcomes. We aim to describe the longer-term respiratory infectious morbidity of infants discharged from NICU using state-wide population-based linked data in Western Australia.

Research

Associations between respiratory and vascular function in early childhood

The link between respiratory and vascular health is well documented in adult populations. Impaired lung function is consistently associated with thicker arteries and higher incidence of cardiovascular disease. However, there are limited data on this relationship in young children and the studies that exist have focussed on populations at high risk of cardiorespiratory morbidity.

News & Events

Annual Community Lecture: You Are What You Breathe

Join us for our Annual Community Lecture entitled "You Are What You Breathe" with Professor Stephen Holgate.

News & Events

Researchers urge caution in how asthma test is used

Researchers are urging caution in the use of a widely accepted test for diagnosing asthma, after their study found it may not be accurate in some settings.

Research

Impact of HIV and antiretroviral drug exposure on lung growth and function over 2 years in an African Birth Cohort

HIV exposure is associated with altered lung function in early life, with a vulnerable HIV-exposed uninfected subgroup based on maternal disease severity

Research

Early life exposure to coal mine fire smoke emissions and altered lung function in young children

Infant exposure to coal mine fire emissions could be associated with long-term impairment of lung reactance

Research

Single-breath washout and association with structural lung disease in children with cystic fibrosis

Acinar ventilation inhomogeneity measured by single-breath washout was not associated with structural lung disease on CT

Research

Mannitol challenge testing for asthma in a community cohort of young adults

We aimed to quantify the diagnostic utility of mannitol challenge testing for asthma in a community cohort and a symptomatic wheezing subset of this cohort.

Research

Persistent activation of interlinked type 2 airway epithelial gene networks in sputum-derived cells from aeroallergen-sensitized symptomatic asthmatics

Our findings provide new insight into the molecular mechanisms operative at baseline in the airway mucosa in atopic asthmatic with natural aeroallergen exposure

Research

The clinical utility of lung clearance index in early cystic fibrosis lung disease is not impacted by the number of multiple-breath washout trials

This study aimed to determine if relationships between LCI and clinical outcomes of CF lung disease differ when only two acceptable MBW trials are assessed.