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Research

Altered attainment of developmental milestones influences the age of diagnosis of rett syndrome

This study describes the attainment of gross developmental milestones and regression, and assesses the relationships between genotype and age at diagnosis.

Research

Pneumococcal conjugate vaccination at birth in a high-risk setting: No evidence for neonatal T-cell tolerance

Concerns about the risk of inducing immune deviation-associated "neonatal tolerance" as described in mice have restricted the widespread adoption...

Research

Prednisolone Versus Dexamethasone for Croup: a Randomized Controlled Trial

The type of oral steroid seems to have no clinically significant impact on efficacy, both acutely and during the week after treatment

Research

The role and therapeutic implications of T cells in cancer of the lung

This review examines the role of T cells in lung cancer, discussing the direction and clinical significance of current and future immunotherapeutic strategies

Research

Hospitalisations for maternal assault are associated with increased risk of child protection involvement

Child maltreatment allegation is common in children following a maternal hospitalisation for assault

Research

Call for a national sore throat guideline

Australia needs a single national pharyngitis guideline to assist in providing rational, consistent and timely antibiotic treatment to patients at high risk of ARF

Research

Innate immune activation occurs in acute food protein–induced enterocolitis syndrome reactions

Food reactions in food protein–induced enterocolitis syndrome are predominantly underpinned by activation of the innate immune system

Research

Spatial clustering of notified tuberculosis in Ethiopia: A nationwide study

Substantial spatial clustering of notified tuberculosis was detected at region, zone and district level in Ethiopia

Research

Longitudinal Cognitive Performance in Individuals at Ultrahigh Risk for Psychosis: A 10-year Follow-up

The onset of psychosis was not associated with deterioration in cognitive ability

Research

Gender-affirming hormones and surgery in transgender children and adolescents

This Review explores the available published evidence on gender-affirming cross-sex hormone and surgical interventions in transgender children