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The Engage Study: discovering and delighting in your baby - a pilot studyAndrew Desiree Gail Kandice Videos Whitehouse Watch and listen to Andrew Silva Alvares Varcin PhD MBBS, FRACP, MPH, PhD PhD M.Psych (Clinical), PhD
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The impact of a Mediterranean diet and physical activity in pregnancy on gestational weight gain and neonatal body composition at birth and 1 year of ageDesiree Silva MBBS, FRACP, MPH, PhD Co-Head, ORIGINS Co-Head, The ORIGINS Project Professor Desiree Silva is Co-Director of ORIGINS and a Professor

The ORIGINS Team is studying early environments and parental physical health and genetics to uncover when and why non-communicable diseases (NCDs) develop.
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Mums Minds MatterAmy Jenny Susan Desiree Keerthi Finlay-Jones Downs Prescott Silva Kottampally BPsych(Hons), MPsych(Clinical), MHealthEcon, PhD (Clin Psych) BApplSci
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Egg-sensitised infants have elevated CD4+ effector memory T regulatory cells from birthIgE-mediated sensitisation to egg is common in infants. In some cases, the processes leading to egg sensitisation are established in early life, even before introduction to solid foods. The underlying mechanisms remain poorly understood.
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Effect of maternal prebiotic supplementation on human milk immunological composition: Insights from the SYMBA studyImmunomodulatory proteins in human milk (HM) can shape infant immune development. However, strategies to modulate their levels are currently unknown. This study investigated whether maternal prebiotic supplementation alters the levels of immunomodulatory proteins in HM.
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Ovalbumin in breast milk is associated with a decreased risk of IgE-mediated egg allergy in childrenShowed for the first time that the presence of an egg-derived allergen in breast milk is associated with a reduced risk of egg allergy in children at 2.5 years of age
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Maternal and family factors and child eating pathology: Risk and protective relationshipsThis study aimed to identify maternal and family factors that may predict increases or decreases in child eating disorder symptoms over time, accounting for...
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The ORIGINS ProjectORIGINS is a new birth cohort study, collecting detailed information about the early environment's influence on a broad range of non-communicable diseases
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Epigenome-wide association study reveals longitudinally stable DNA methylation differences in CD4+ T cells from children with IgE-mediated food allergyFood allergy is mediated by a combination of genetic and environmental risk factors, potentially mediated by epigenetic mechanisms.