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Wheezing and asthma exacerbations are leading causes of pediatric hospital admissions. Predicting which children will experience persistent exacerbations remains challenging. Prior research has identified immune endotypes in the nasal epithelium of children with acute asthma and wheezing, characterized by varying balances of interferons and inflammatory markers. Notably, children exhibiting low interferon responses coupled with high inflammation are at an increased risk for recurrent respiratory exacerbations.
Britta Regli-von Ungern-Sternberg AM FAHMS MD, PhD, DEAA, FANZA Chair of Paediatric anaesthesia, University of Western Australia; Consultant
Heart valve disease (HVD) can cause morbidity and impairment of quality of life (QOL) both before and after intervention. However, descriptions of the QOL of people with HVD across the disease course are limited. We aimed to collect the experience of people living with HVD through qualitative interviews, focusing on how HVD impacts their self-perceived QOL.
Nonvital pulp therapy is a treatment option that can preserve pathologically affected primary teeth and contribute to space maintenance. This retrospective case series examined the healing effects in infected primary teeth after pulpectomy using mineral trioxide aggregate obturation and eruption characteristics of the succedaneous teeth.
The rates of obesity and type 1 diabetes (T1D) in children and adolescents are increasing in many settings worldwide, but data on weight gain in this group are limited in New Zealand. We examined temporal body mass index (BMI) changes and associated factors in young people with T1D in a mixed urban-rural region.
Online sports betting has become a profitable segment of the global gambling industry, with young men identified as the demographic most likely to engage in online sports betting and at risk of gambling problems.
To characterize sleep profiles in individuals with neurogenetic disorders (NGDs) and examine the contribution of key clinical and psychiatric symptoms to these profiles.
University students face obstacles while pursuing their goals, and these challenges risk undermining their mental health. Goal flexibility has been identified as beneficial for promoting well-being and protecting mental health; however, the relationship between goal flexibility and mental health challenges remains underexplored.
Conversion practices (sometimes referred to as 'conversion therapy') refer to interventions that aim to change a person's sexual orientation or gender identity. While these are often associated with faith-based settings, they can also occur in secular healthcare contexts. The practices are associated with significant psychological harm.
There is a lack of digital gatekeeper resources developed for parents to assist them in recognising and responding to mental health problems in their children and adolescents. We aimed to address this by exploring parents' mental health information needs, and to iteratively develop and design a resource incorporating their feedback.