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Research
Transcriptome Analysis Uncovers a Growth-Promoting Activity of Orosomucoid-1 on HepatocytesOrm1 is induced in response to hepatic injury and executes liver regeneration by activating cell cycle progression in hepatocytes
Research
Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLCEpigenetically regulated genes have a great theranostic potential, especially in tumors with no apparent driver mutations.
Research
Gene editing and cardiac disease modelling for the interpretation of genetic variants of uncertain significance in congenital heart diseaseGenomic sequencing in congenital heart disease (CHD) patients often discovers novel genetic variants, which are classified as variants of uncertain significance (VUS). Functional analysis of each VUS is required in specialised laboratories, to determine whether the VUS is disease causative or not, leading to lengthy diagnostic delays.
News & Events
Research at CliniKidsAt CliniKids, it is important that the services we offer are informed by the children and families that utilise our services.
News & Events
Autism Month!April is Autism Month and to mark the occasion, we’re transforming our reception desk in the clinic to an AMAZING wall for our families to contribute to.
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Client support at CliniKidsNicki, Leah, Tracy, and Amy make up our wonderful Client Support team at CliniKids. The team was established in mid-2021 as services began to grow.
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Frangipani Family Day a huge success!CliniKids held its inaugural Frangipani Family Day recently – an event organised to honour the wonderful contribution of its much loved and dearly missed colleague, the late Kate Sorensen.
Research
The course and prognostic capability of motor difficulties in infants showing early signs of autismDelays within the motor domain are often overlooked as an early surveillance marker for autism. The present study evaluated motor difficulties and its potential as an early predictive marker for later autism likelihood in a cohort of infants showing early behavioral signs of autism aged 9-14 months. The motor domain was evaluated using the motor subscales of the Mullen Scales of Early Learning at baseline, and at a 6-month follow-up.
Research
Content validation of common measures of functioning for young children against the International Classification of Functioning, Disability and Health and Code and Core Sets relevant to neurodevelopmental conditionsYoung children who have developmental delay, autism, or other neurodevelopmental conditions can have difficulties doing things in different areas of their life. What they can and cannot do is called their level of functioning. There are lots of assessment measures that aim to assess functioning.
Research
Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adultsEpigenetic changes at the GFI1 were linked to smoking exposure in-utero/in-adulthood and robustly associated with cardio-metabolic risk factors
Research
Co-occurring intellectual disability and autism: Associations with stress, coping, time use, and quality of life in caregiversHaving a child on the autism spectrum (AS) is known to impact caregiver quality of life (QoL), time use, and stress. A co-occurring diagnosis of intellectual disability (ID) is common among children on the autism spectrum, with ID itself impacting caregiver outcomes. This study sought to understand how co-occurring ID in children on the autism spectrum may influence caregiver-related outcomes. Secondary analysis of survey data from caregivers of 278 children on the autism spectrum with (n = 62) and without (n = 216) co-occurring ID was conducted, exploring impacts on caregiver QoL, stress, coping, and time-use.
News & Events
Computer algorithm links facial masculinity to autismA new study led by The Kids Research Institute Australia has found a link between masculine facial features and autism.
News & Events
Frangipani for KateThank you to Dave and Marieke Taylor of the Rotary Club of Scarborough who have donated a frangipani tree from their own garden to CliniKids to honour our late colleague, Kate Sorensen.
News & Events
One-of-a-kind autism service offers new hope to familiesWestern Australian babies and children with autism and developmental delay will be able to access world-first therapies and interventions backed by the latest research, thanks a unique clinical service developed by The Kids Research Institute Australia.